Grover's disease, despite histological similarity to Darier's disease, does not share an abnormality in the ATP2A2 gene

J Powell, A Sakuntabhai, M James… - British Journal of …, 2000 - academic.oup.com
J Powell, A Sakuntabhai, M James, S Burge, A Hovnanian
British Journal of Dermatology, 2000academic.oup.com
A 12-year-old girl with localized stable vitiligo was treated by epidermal grafting. Blisters on
the recipient site formed within 24h after three freeze±thaw cycles with liquid nitrogen.
Blisters on the donor site were made by suction on the inner portion of the thigh. After
approximately 3 h of suction at 200 mmHg, large unilocular bullae appeared. After removal
of the blisters at the recipient site, the epidermal sheets were grafted to the denuded
recipient site and held in place. Two weeks after grafting, once weekly systemic psoralen …
A 12-year-old girl with localized stable vitiligo was treated by epidermal grafting. Blisters on the recipient site formed within 24h after three freeze±thaw cycles with liquid nitrogen. Blisters on the donor site were made by suction on the inner portion of the thigh. After approximately 3 h of suction at 200 mmHg, large unilocular bullae appeared. After removal of the blisters at the recipient site, the epidermal sheets were grafted to the denuded recipient site and held in place. Two weeks after grafting, once weekly systemic psoralen-ultraviolet A treatment was started. Almost complete repigmentation was observed 3 months after grafting. Four months after grafting, the patient noticed two verrucous plaques in the grafted site (Fig. 1). She denied warts on any other body sites. There was no history of similar lesions in her family or close friends. The operator, who wore gloves, had a verrucous papule on his hand during the surgery. Skin biopsy of two different lesions, on the patient's back and the operator's hand, demonstrated histological features of verruca vulgaris. Human papillomavirus (HPV) typing was not performed.
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